Penfluridol

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Penfluridol
Systematic (IUPAC) name
1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
Identifiers
CAS number 26864-56-2
ATC code N05AG03
PubChem 33630
Chemical data
Formula C28H27ClF5NO 
Mol. mass 523.965
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Penfluridol is a piperidine antipsychotic. It was discovered at Janssen Pharmaceutica in 1968.

[edit] References

  • Janssen PA, Niemegeers CJ, Schellekens KH, Lenaerts FM, Verbruggen FJ, Van Nueten JM, Schaper WK., The pharmacology of penfluridol (R 16341) a new potent and orally long-acting neuroleptic drug, Eur J Pharmacol. 1970 Jul 15;11(2):139-54.
  • van Praag HM, Schut T, Dols L, van Schilfgaarden R., Controlled trial of penfluridol in acute psychosis,

Br Med J. 1971 Dec 18;4(5789):710-3.


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