Talk:Pattern recognition receptor
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[edit] PAMPs
To avoid getting into an edit war, I'd like to ask for the view of other editors on the subject of PAMPs. It seems that one editor opposes the use of pathogen-associated molecular patterns (or PAMPs) in this article (and in the Toll-like receptor page) and wishes to replace this expression with microbial-associated molecular patterns (MAMPs). My view is that the PAMPs term is widely used in existing literature and is currently the accepted terminology for ligands of TLRs, so it should not be completely removed from this page or the TLR page. At the moment there is little reference to MAMPs, (in fact I did find 2 very recent articles referring to these,[1][2] but no other references) so to avoid confusion, I agree this term could be introduced here, but not at the complete exclusion of PAMPs. Could other people please leave their comments on this? Ciar 03:39, 26 February 2007 (UTC)
- ^ Mackey D, McFall A (2006). "MAMPs and MIMPs: proposed classifications for inducers of innate immunity". Mol Microbiol 61 (6): 1365-71. PMID 16899081.
- ^ Swerdlow M, Kennedy D, Kennedy J, Washabau R, Henthorn P, Moore P, Carding S, Felsburg P (2006). "Expression and function of TLR2, TLR4, and Nod2 in primary canine colonic epithelial cells". Vet Immunol Immunopathol 114 (3-4): 313-9. PMID 17027090.
- current usage should be used in Wikipedia. Wikipedia is not a battlefield for warring academics over linguistics and terminology.--ZayZayEM 06:31, 5 March 2007 (UTC)
