P2
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- P2
- Alfa Romeo P2 iconic 1920s racing automobile
- Intel Pentium II 6th generation central processing unit
- Intel 80286 2nd generation processor architecture
- LNER Class P2 locomotive designed by Sir Nigel Gresley
- P2 biological confinement level
- P2 Former designation of Nix, a moon of Pluto
- P-2 Hawk, a bi-plane fighter of the U.S. Army Air Corps
- P2, Honda robot one of the series of Honda robots, an ASIMO predecessor
- P-2 Neptune aircraft
- P2 receptor, a purinergic and pyrimidinergic cell surface receptor
- P2 (storage media), "Professional Plug-in" solid state data storage technology employed by Panasonic
- P2, Stagehand
- P2 Sveriges Radio chanel, playing classical music, jazz and world music
- P2 Train Map and describer system used in the United Kingdom, built by Atos Origin
- P2 virus - a fictional virus in The Second Angel that suffocates it's victims by blocking the hemoglobin's oxygen uptake in the blood.
- Period 2 of the periodic table
- Pilatus P-2 aircraft
- Prodrive P2, an automobile built by Prodrive
- P2 Masonic Lodge or 'Propaganda Due', an Italian pseudo-Masonic lodge involved in a financial scandal with the Vatican Bank and accused of cooperation with the underground NATO organisation Gladio
- Undernet P2 (Philosophy2) channel on the IRC network
- UTair (IATA airline designator P2)