P16INK4a
From Wikipedia, the free encyclopedia
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
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Identifiers | |
Symbol | CDKN2A CDKN2, MLM |
HUGO | 1787 |
Entrez | 1029 |
OMIM | 600160 |
RefSeq | NM_000077 |
UniProt | P42771 |
Other data | |
Locus | Chr. 9 p21 |
- The correct title of this article is p16INK4a. The initial letter is shown capitalized due to technical restrictions.
p16INK4a is a principle product of the INK4 gene. Its alternate reading frame product is p14ARF. p16INK4a regulates the cell cycle by binding and deactivating various cyclin-CDK complexes.
[edit] External links
- p16INK4a description at Entrez Gene
- "Scientists study mammalian aging" at upi.com
- "p16INK4a induces an age-dependent decline in islet regenerative potential" at nature.com