Overactive bladder
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| ICD-10 | N32.8 |
|---|---|
| ICD-9 | 596.51 |
Overactive bladder (OAB) is a chronic urological condition defined by a set of symptoms: "urgency, with or without urge incontinence, usually with frequency and nocturia." The International Continence Society (ICS) is responsible for this definition. The etiology (cause) of OAB is unclear, but involves dysfunction of the detrusor muscle. OAB does not include stress urinary incontinence.
It has been estimated from surveys that about one in six adults in the United States or Europe has symptoms of OAB.[1][2] Based on this, it is believed that over 33 million adults in the United States have OAB.[3] The prevalence of OAB increases with age and is similar in women and men.[1] Because the average age of people in the developed world is increasing, it is expected that OAB will become more common in the future.
Treatment for OAB includes lifestyle modification (fluid restriction, avoidance of caffeine), bladder retraining, antimuscarinic drugs (darifenacin, hyoscyamine, oxybutynin, tolterodine, solifenacin, trospium), and various devices (Urgent PC Neuromodulation System, InterStim). The antimuscarinic fesoterodine was recommended for approval by the European Medicines Agency in February 2007, but is not yet available for use.
[edit] References
- ^ a b Stewart WF, Van Rooyen JB, Cundiff GW, Abrams P, Herzog AR, Corey R, Hunt TL, Wein AJ. Prevalence and burden of overactive bladder in the United States World Journal of Urology 2003 May;20(6):327-36..
- ^ Milsom I, Abrams P, Cardozo L, Roberts RG, Thuroff J, Wein AJ. How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study. BJU Int. 2001 Jun;87(9):760-6.
- ^ Definition and epidemiology of overactive bladder. Urology (2002).
