Osmolal gap
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Osmolal Gap is the difference between measured serum osmolality and calculated serum osmolality.
It is typically calculated as: OG = measured serum osmolality - (2 X serum sodium + serum glucose + serum urea)
Where:
- 2 X serum sodium + serum glucose + serum urea = the calculated serum osmolality and all measures are in mmol/L.
- OG = osmolal gap
In US customary units the calculated osmolarity is: ( 2 x sodium ) + glucose/18 + BUN/2.8.
A normal osmolal gap is < 12 mmol/L.
Causes of an elevated osmolal gap are numerous. Several causes are:
- ethanol intoxication
- methanol ingestion
- ethylene glycol ingestion
[edit] See also
[edit] External links
- Osmolar gap - fpnotebook.com
- Serum Osmolality - fpnotebook.com
- Acid-Base Physiology