Organopalladium

Organopalladium chemistry is a branch of organometallic chemistry that deals with organic palladium compounds and their reactions. Palladium is often used as a catalyst in the reduction of alkenes and alkynes with hydrogen. This process involves the formation of a palladium-carbon covalent bond. Palladium is also prominent in carbon-carbon coupling reactions, as demonstrated in tandem reactions.

[edit] Organopalladium chemistry timeline.

1873 - A. N. Zaitsev reports reduction of benzophenone over palladium with hydrogen.
1894 - Phillips reports that palladium(II) chloride reduces to palladium metal by contact with ethylene.
1907 - Autoclave technology introduced by W. Ignatieff makes it possible to carry out high pressure hydrogenation.
1956 - In the Wacker process ethylene and oxygen react to acetaldehyde with catalyst PdCl₂/CuCl₂
1972 - The Heck reaction is a coupling reaction of a halogenide with an olefine. The catalyst is Pd(0).
1973 - The Trost asymmetric allylic alkylation is a nucleophilic substitution.
1975 - The Sonogashira coupling is a coupling reaction of terminal alkynes with aryl or vinyl halides.