Talk:Nuclear lamina
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Article Grading: The following comments were left by the quality and importance raters: (edit ยท refresh) I've changed the importance rating on this article from low to mid based on a lot of research done on the nuclear lamina within the last few years spurred by medical interest in the wake of the discovery of laminopathies. - tameeria 02:15, 10 February 2007 (UTC) |
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[edit] A few corrections...
I've made a few clarifications/corrections to the article:
- Lamins are present in animals only, but are not present in plants or fungi (though plants may have a lamina-like structure made up of other proteins). I'll search for a good reference to add this information to the article.
- Laminin is a protein of the basal lamina, not the nuclear lamina - corrected to lamin.
- ZMPSTE24 is a zinc metalloprotease, not a lamin - replaced with actual lamin genes (LMNA, LMNB1). (ZMPSTE24 is involved in processing prelamin A into mature lamin, so its mutation causes defects in the lamina, but that is a different mechanism from a mutated lamin gene.)
- Since the article on Laminopathies contains a more complete set of references on associated diseases, I took out the two references here as they didn't represent the full picture but only two examples.
- tameeria 01:36, 9 February 2007 (UTC)
[edit] Importance
I've changed the importance rating on this article from low to mid. The reason for this is that within the last five+ years, a lot of research work has been done on the nuclear lamina, spurred by medical interest in the wake of the discovery of laminopathies including Emery-Dreifuss muscular dystrophy and Hutchinson-Gilford progeria syndrome. - tameeria 02:13, 10 February 2007 (UTC)
