Normal anion gap acidosis
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In renal physiology, normal anion gap acidosis, and less precisely non-anion gap acidosis, is an acidosis that is not accompanied by an anion gap.
The differential diagnosis of normal anion gap acidosis is relatively short (when compared to the differential diagnosis of acidosis):
- Hyperalimentation
- Acetazolamide and other carbonic anhydrase inhibitors
- Renal tubular acidosis
- Diarrhea
- Ureteroenteric fistula
- Pancreaticoduodenal fistula
It can be rememebered with the mnemonic HARD-UP.
The most common cause of normal anion gap acidosis is diarrhea.