Talk:NMDA receptor
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The structure section was misleading and out of date. The multimeric NMDA receptor protein contains four subunits, although once it was thought that five subunits were present, as for a muscle nicotinic receptor. However, glutamate receptors are more closely related to potassium channels and share their tetrameric arrangment. These subunits are the products of up to 8 different genes. It is a nice idea to mention structural features of the protein, which is why I added the part about the ligand binding domain. I think that this page needs more updating, and so I will proceed with caution and make a few changes Aplested 13:31, 22 Sep 2004 (UTC)
Most of this article is lifted from the abstract of the Liu and Yang paper in the external link section. Not really well known or quoted, certainly not a patch on the Dingledine review, which has the benefit of being freely available. Aplested 13:51, 22 Sep 2004 (UTC)
Just added a link to the Long-term potentiation thought that it is quite relevant. -- Amelvin 22:40, 13 May 2006 (UTC)
I've been studying receptors and I haven't found any info on wiki about PCP receptors. I read at http://www.esi-topics.com/schizophrenia/interviews/Dr-Daniel-Javitt.html that PCP receptars are a part of NMDA receptors. I think that should be mentioned in this article and searches for PCP receptors should link here. Eddietoran 05:51, 13 October 2006 (UTC)
Although PCP is an NMDA receptor antagonist (PCP makes the receptor unable to activate) it also binds to D2 dopamine receptors and 5-HT2 serotonin receptors. Pages that discuss PCP should then link to the pages of these receptors. Sciencepixie 17:36, 14 March 2007 (UTC)
Reference: Molecular Psychiatry 2002, Volume 7, Number 8, Pages 837-844
