NK1 receptor antagonist
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Neurokinin NK1 antagonists are a novel class of medications that possesses unique antidepressant[1], anxiolytic[2], and antiemetic properties.
The NK2 and NK3 receptors are also targets for novel classes of medications, and also show prominent antidepressive and anxiolytic effects.[3]
[edit] References
- ^ The antidepressant-like effects of neurokinin NK1 receptor antagonists in a gerbil tail suspension test.
- ^ The gerbil elevated plus-maze II: anxiolytic-like effects of selective neurokinin NK1 receptor antagonists.
- ^ Selective blockade of NK2 or NK3 receptors produces anxiolytic- and antidepressant-like effects in gerbils.
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