Nicocodeine
From Wikipedia, the free encyclopedia
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Nicocodeine
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| Systematic (IUPAC) name | |
| ? | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C24H24N2O4 |
| Mol. mass | 404.458 g/mol |
| Synonyms | Nicocodine, 6-Nicotinoylcodeine, Lyopect, Tusscodin |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | Oral, intravenous |
Nicocodeine (Lyopect®, Tusscodin®) is an opiate derivative developed as a cough suppressant and analgesic. It is not commonly used, but has activity similar to other opiates. Nicocodeine is metabolised in the liver by demethylation to produce 6-nicotinoylmorphine, and subsequently further metabolised to morphine. Side effects are similar to those of other opiates and include itching, nausea and respiratory depression.
CAS number of hydrochloride: 58263-01-7
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