Neuroprotection

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The term neuroprotection means mechanisms within the nervous system which protect neurons from apoptosis or degeneration, for example following a brain injury or as a result of chronic neurodegenerative diseases. The word derives from the words "neuron" (Greek for nerve cell) and "protection" (Latin for "saving").

Nowadays there's a broad interest in how apoptosis and neuroprotection act on the brain in situations as different as growing up and learning or being ill (stroke, schizophrenia, Parkinson's disease).

A recent post-mortem study of the anterior cingulate cortex of persons with schizophrenia found increased levels of cellular signaling proteins, primarily PEBP, that may lead to increased levels of neuroprotection. (Clark, 2006)

[edit] References

• Clark, D., Dedova, I. Cordwell, S., Matsumoto, I. (2006). A proteome analysis of the anterior cingulate cortex gray matter in schizophrenia. Molecular Psychiatry, 11, 459–470.