Neuromodulators

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Neuromodulators modulate regions or circuits of the brain. That is, they affect a group of neurons, causing a modulation of that group's functioning. In contrast, neurotransmitters convey information from one neuron to another (or from a neuron to another cell, such as a muscle cell). But many neuromodulators do also act as neurotransmitters.

Examples of neuromodulators are substance P (pain perception) and endorphins (pain killers).

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