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[edit] Summary
Description |
The structure of neprilysin, a zinc metalloprotease involved in the metabolism of extracellular regulatory peptides such as the enkephalins and substance P. Neprilysin in neural tissue is the major protease degrading amyloid beta, a peptide fragment whose abnormal misfolding and aggregation is associated with Alzheimer's disease. The gray sphere represents a zinc atom; the green structure is a zinc-chelating enzyme inhibitor.
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Source |
Self-created from PDB ID 1R1H using PyMol
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Date |
7 Mar 2007
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Author |
Opabinia regalis
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Permission |
GFDL
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[edit] Licensing
I, the author of this work, hereby publish it under the following license:
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