N-Methylmorpholine N-oxide

From Wikipedia, the free encyclopedia

N-Methylmorpholine N-oxide
Identifiers
CAS number	[7529-22-8]
SMILES	CN+1(O-)CCOCC1
Properties
Molecular formula	C5H11NO2
Molar mass	117.15 g/mol
Melting point	180 - 184 °C
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

N-Methylmorpholine-N-oxide or NMO is an organic compound. This heterocyclic amine oxide and morpholine derivative is used in organic chemistry as a co-oxidant and sacrificial catalyst in oxidation reactions for instance in osmium tetroxide oxidations and the Sharpless asymmetric dihydroxylation or oxidations with TPAP. NMO is commercially supplied as a monohydrate C₅H₁₁NO₂.H₂O

NMO is used as a solvent for Lyocell manufacturing.

Oxidation of an alkene with osmium tetroxide (0.06 eq.) and NMO (1.2 eq.)in acetone/water 5:1 RT 12 hrs.^[1]

[edit] References

1. ^ Preparation of 3H-Pyrrolo2,3-cisoquinolines and 3H-Pyrrolo2,3-c [2,6]- and 3H-Pyrrolo2,3-c [1,7]-naphthyridines U. Narasimha Rao, Xuemei Han and Edward R. Biehl Arkivoc 2002 (x) 61-66 Online Article