Mycobacterium fortuitum

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Mycobacterium fortuitum

Scientific classification

Kingdom:	Bacteria
Phylum:	Actinobacteria
Order:	Actinomycetales
Suborder:	Corynebacterineae
Family:	Mycobacteriaceae
Genus:	Mycobacterium
Species:	M. fortuitum

Binomial name

Mycobacterium fortuitum
Da Costa Cruz 1938, ATCC 6841

Mycobacterium fortuitum

1 Description
2 Pathogenesis
3 Type Strain
4 References

[edit] Description

Gram-positive, nonmotile and acid-fast rods (1-3µm x 0.2-0.4µm). Sometimes long rods with occasional beaded or swollen cells having non-acid-fast ovoid bodies at one end.

Colony characteristics

Smooth hemispheric colonies, usually off-white or cream colored colonies. May be butyrous, waxy, multilobate and even rosette clustered (dilute inocula).
On Malachite green containing media, such as Löwenstein-Jensen media, colonies can absorb the green dye.

Physiology

Rapid growth on Löwenstein-Jensen media within 2-4 days.
No growth at 45°C, but grows on MacConkey agar

Differential characteristics

Differentiation from M. fortuitum subsp. acetamidolyticum by its ability to utilise L-glutamate and its inability to utilise acetamide as simultaneous nitrogen and carbon source. Both subspecies share an identical 5'-16S rDNA sequence. However, the ITS sequences are different.

[edit] Pathogenesis

Different types of sporadic infections: pulmonary disease, local abscesses.
Postoperative sternal wound infections, endocarditis, meningitis, and osteomyelitis.
Has produced postoperative infections after breast augmentation surgury.
Biosafety level 2

[edit] Type Strain

Found world wide in soil, dust, rivers, lakes and tap water.
First isolated from a 25-year old patient (syringe abscess) in Rio de Janeiro.
Also isolated from lymph glands of cattle and systemic or nodular infection of frogs.

Strain ATCC 6841 = CCUG 20994 = CIP 104534 = DSM 46621 = IFO (now NBRC) 13159 = JCM 6387 = NCTC 10394.

Subsequently, this species has been divided into subspecies M. fortuitum subsp. acetamidolyticum

[edit] References

Da Costa Cruz, J. 1938. Mycobacterium fortuitum um novo bacillo acidoresistance pathogenico para o homen. Acta Medica (Rio de Janeiro), 1, 297-301.]