Mycobacterium cookii

From Wikipedia, the free encyclopedia

Mycobacterium cookii
Scientific classification
Kingdom: Bacteria Phylum: Actinobacteria Order: Actinomycetales Suborder: Corynebacterineae Family: Mycobacteriaceae Genus: Mycobacterium Species: M. cookii
Binomial name
Mycobacterium cookii Kazda et al. 1990, ATCC 51304

Mycobacterium cookii

Contents 1 Description 2 Pathogenesis 3 Type Strain 4 References

[edit] Description

Gram-positive, nonmotile and polymorphic acid-fast rods (0.8µm x 1.4µm – 1.9µm). Forms clumps, but not cords or cross bands. Does not form spores, capsules and aerial hyphae.

Colony characteristics

• Colonies are smooth and glistening with yellow-orange pigmentation (0.5–1.0 mm diameter, scotochromogenic).

Physiology

• Slow growth on Löwenstein-Jensen medium or Middlebrook 7H10 agar at 31°C (optimal temperature). No growth at 37°C, 42°C or 45°C.
• Most of the strains are susceptible to ethambutol, isoniazid, streptomycin, and rifampin.

Differential characteristics

• Phylogenetic position between the slowly growing pathogenic species and the saprophytic rapidly growing species by partial 16S rDNA sequencing.

[edit] Pathogenesis

• Not pathogenic for humans, mice, guinea pigs and rabbits. Biosafety level 1.
• Provokes a non-specific hypersensitivity reaction to bovine tuberculin.

[edit] Type Strain

Strain NZ2 = ATCC 49103 = CIP 105396 = DSM 43922 = JCM 12404.

[edit] References

• Kazda et al. 1990. Mycobacterium cookii sp. nov. Int. J. Syst. Bacteriol.,40, 217-223.