Muscle fiber

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Global view of a neuromuscular junction:
1. Axon
2. Neuromuscular junction
3. Muscle fiber
4. Myofibril

A top-down view of skeletal muscle

A muscle fiber, also spelled muscle fibre (see spelling differences), also technically known as a myocyte, is a single cell of a muscle. Muscle fibers contain many myofibrils, the contractile unit of muscles. Muscle fibers are very long; a single fiber can reach a length of 30cm.

Muscle fibres can be grouped according to what kind of tissue they are found in -- skeletal muscle, smooth muscle, and cardiac muscle. The muscle cells of heart muscle tissue are called cardiomyocytes.

1 Skeletal muscle fibers
2 Type I
3 Type II
4 Type III
5 See also
6 External links

[edit] Skeletal muscle fibers

Skeletal muscle fibers can be further divided into two basic types, type I (slow-twitch fibers) and type II (fast-twitch fibers). Type II is further divided, as follows:

type	Type I	Type IIa	Type IIb
Description	slow oxidative (SO) fibers	fast oxidative-glycolytic (FOG)	fast-twitch glycolytic fibers
myoglobin	high	medium	low
mitochondria	many	moderate	few
fatigues?	slowly	moderate speed	fast
color	red	red	white
diameter	narrow	medium	wide

[edit] Type I

Type I muscle fibers (slow-oxidative fibers) use primarily cellular respiration and, as a result, have relatively high endurance. To support their high-oxidative metabolism, these muscle fibers typically have lots of mitochondria and myoglobin, and thus appear red or what is typically termed "dark" meat in poultry. Type I muscle fibers are typically found in muscles of animals that require endurance, such as chicken leg muscles or the wing muscles of migrating birds (e.g., geese).

[edit] Type II

Type II muscle fibers use primarily anaerobic metabolism and have relatively low endurance. These muscle fibers are typically used during tasks requiring short bursts of strength, such as sprints or weightlifting. Type II muscle fibers cannot sustain contractions for significant lengths of time, and are typically found in the white meat (e.g., the breast) of chicken.

There are three sub-classes of type II muscle fibers, type IIa (Fast-Oxidative), IIb (Fast-Glycolytic), and type IIc. The Type IIa fast-oxidative fibers actually also appear red, due to their high content of myoglobin and mitochondria. Type IIb (Fast-Glycolytic) are the fastest twitch and most powerful, twitching in upwards of 120 times per second. They also tire the fastest, and are given as the fight or flight to sedentary individuals (about 16.4 percent of total). They also are the fiber type of choice to a power lifter. These fibers appear white histologically, due to their low oxidative demand, manifested by the lack of myoglobulin and mitochondria (relative to the Type I and Type IIa fibers). Type IIc are created from a fusion of satellite cells to the corrupted Type IIb, so long as the cortisone hormone is inhibited, and offer the attributes of both Type IIa and Type IIb. The biochemical difference between the three types of muscle fibers is their myosin heavy chains.

[edit] Type III

These are also called the "intermediate fast-twitch fibers". They are a cross between Type I and Type IIb. They can utilize both aerobic and anaerobic pathways for energy metabolism.