Milas hydroxylation
From Wikipedia, the free encyclopedia
Milas hydroxylation is an organic reaction converting an alkene to a vicinal diol, and was developed by N. A. Milas in the 1930's.[1] The cis-diol is formed by reaction of alkenes with Hydrogen peroxide and either ultraviolet light or a catalytic Osmium, Vanadium, or Chromium oxide.
The reaction was superseeded in synthetic chemistry by the Upjohn dihydroxylation and later by the Sharpless asymmetric dihydroxylation.
[edit] References
- ^ N. A. Milas et al., J. Am. Chem. Soc. 1936 1302 (DOI:10.1021/ja01298a065)
[edit] See also
- Upjohn Dihydroxylation
- Sharpless dihydroxylation
