Methylergonovine

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Methylergonovine
Chemical name	9,10-didehydro-N-[1-(hydroxymethyl)- propyl]-D-lysergamide
Chemical formula	C₂₀H₂₅N₃O₂
Molecular mass	339.42
Melting point	172
CAS numbers	113-42-8
SMILES	CC[C@@H](CO)NC(=O)[C@@H] 2/C=C1/c3cccc4N\C=C (\C[C@H]1N(C)C2)c34

Methylergonovine, also known as methylergometrine, methylergobasin, and d-lysergic acid 1-butanol amide, is a synthetic analogue of ergonovine, a psychedelic alkaloid found in ergot, and many species of morning glory. It is a member of the ergoline family and chemically similar to LSD, ergine, ergonovine, and lysergic acid. Due to its oxytocic properties, it has a medical use in obstetrics. According to Jonathan Ott, methylergonovine has LSD-like actions above 2 milligrams. Clinical dosages are ten times lower.

[edit] Obstetric Use

Methergine (methylergonovine maleate) is a blood vessel constrictor and smooth muscle agonist most commonly used to prevent or control excessive bleeding following childbirth and spontaneous or elective abortion. It also causes uterine contractions to aid in expulsion of retained products of conception after a missed abortion (miscarriage in which all or part of the fetus remains in the uterus) and to help deliver the placenta after childbirth. It is available as tablets or injection (IM or IV).