Methdilazine


Methdilazine
Systematic (IUPAC) name
10-[(1-methylpyrrolidin-3-yl) methyl]- 10H-phenothiazine
Identifiers
CAS number	1982-37-2
ATC code	R06AD04
PubChem	14677
DrugBank	APRD00713
Chemical data
Formula	C₁₈H₂₀N₂S
Mol. mass	296.431 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Methdilazine is an antihistamine.

[edit] External links

Rani Basu L, Mazumdar K, Dutta N, Karak P, Dastidar S (2005). "Antibacterial property of the antipsychotic agent prochlorperazine, and its synergism with methdilazine". Microbiol Res 160 (1): 95–100. PMID 15782943.
Chattopadhyay D, Mukherjee T, Pal P, Saha B, Bhadra R (1998). "Altered membrane permeability as the basis of bactericidal action of methdilazine". J Antimicrob Chemother 42 (1): 83–6. PMID 9700532.
Chattopadhyay D, Dastidar S, Chakrabarty A (1988). "Antimicrobial properties of methdilazine and its synergism with antibiotics and some chemotherapeutic agents". Arzneimittelforschung 38 (7): 869–72. PMID 2905130.

v • d • e Antihistamines (primarily R06)
Aminoalkyl ethers	Bromazine, Carbinoxamine, Clemastine, Chlorphenoxamine, Diphenylpyraline, Diphenhydramine, Doxylamine
Substituted alkylamines	Brompheniramine, Chlorphenamine, Dexbrompheniramine, Dexchlorpheniramine, Dimetindene, Pheniramine, Talastine
Substituted ethylene diamines	Chloropyramine, Histapyrrodine, Mepyramine, Methapyrilene, Pyribenzamine
Phenothiazine derivatives	Alimemazine, Hydroxyethylpromethazine, Isothipendyl, Mequitazine, Methdilazine, Oxomemazine, Promethazine
Piperazine derivatives	Buclizine, Cetirizine, Chlorcyclizine, Cinnarizine, Cyclizine, Hydroxyzine, Levocetirizine, Meclozine, Niaprazine, Oxatomide
Others for systemic use	Acrivastine, Antazoline, Astemizole, Azatadine, Azelastine, Bamipine, Cyproheptadine, Deptropine, Desloratadine, Ebastine, Epinastine, Ketotifen, Loratadine, Mebhydrolin, Mizolastine, Phenindamine, Pimethixene, Pyrrobutamine, Rupatadine, Terfenadine, Triprolidine
For topical use	Bamipine, Chloropyramine, Chlorphenoxamine, Clemastine, Dimetindene, Diphenhydramine, Isothipendyl, Mepyramine, Promethazine, Thenalidine
Antiallergic agents excluding corticosteroids	Antazoline, Azelastine, Fexofenadine
Other antiallergics	Emedastine, Epinastine, Ketotifen, Olopatadine