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A megakaryoblast is a precursor cell to a promegakaryocyte, which in turn becomes a megakaryocyte. It is the beginning of the thrombocytic series.
It derives from an CFU-Me colony unit of pluripotential hemopoietic stem cells.
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Blood |
Plasma |
Hematopoietic stem cells - Red blood cells (Reticulocyte, Normoblast) - White blood cells |
Lymphoid |
T cells: Cytotoxic CD8+, Helper CD4+/Regulatory, γδ, Natural Killer T cell
B cells: Plasma, Memory
Natural killer cells |
Myeloid |
Granulocytes (Neutrophil, Eosinophil, Basophil) - Mast cell precursors
Dendritic cells (Langerhans cells) - Monocytes/Macrophages (Histiocytes, Kupffer cells, Langhans giant cells, Microglia, Osteoclasts)
Megakaryoblast - Megakaryocyte - Platelets |