Mecloqualone

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Mecloqualone (Nubarene) is an analogue of methaqualone which was first made in 1960 [1] and marketed mainly in France and some other european countries. It has sedative, hypnotic and anxiolytic properties, and was used for the treatment of insomnia. [2] Mecloqualone is faster acting but shorter lasting than methaqualone and so was used only as a sleeping pill[3], in contrast to methaqualone which was used as a general purpose anxiolytic as well. Mecloqualone was never as widely used as methaqualone and is no longer prescribed because of concerns about its potential for abuse and overdose.

Image:mecloqualone.png

3-(2-chlorophenyl)-2-methyl-quinazolin-4-one

CAS number 340-57-8

[edit] See Also

[edit] References

  1. ^ Jackman GV, Petrow V, Stephenson O. Journal of Pharmacy and Pharmacology 1960; 12(9):528-9
  2. ^ Mouren P, Giraud F, Pinsard N. Clinical use of a new psycholeptic: Mecloqualone. (French) Marseille Medical. 1963;100: 599-602.
  3. ^ Dubnk B, Towne CA, Bush MT. Detection, assay and rate of excretion of mecloqualone in animals and man. Toxicology and Applied Pharmacology. 1969 Nov;15(3):632-41.
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