MAP kinase kinase kinase

MAP kinase activation
Mitogen
↓
MAP kinase kinase kinase (MAP3K or MKKK)
↓
MAP kinase kinase (MAP2K or MKK)
↓
MAP kinase
↓
further signalling

MAP kinase kinase kinase (or MAP3K) is a serine/threonine-specific protein kinases in which acts upon MAP kinase kinase.

There are 15 genes:

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