User talk:Lwollert

From Wikipedia, the free encyclopedia

You have new messages (last change).

Hi, Lwollert, welcome to WikiProject LGBT Studies!

We are a growing community of Wikipedia editors dedicated to identifying, categorizing, and improving articles of interest to the LGBT community. Some points that may be helpful:

  • Our main aim is to help improve LGBT-related articles, so if someone asks for help with an article, please try your hardest to help them if you are able.
  • Most important discussions take place on the project's main discussion page; it is highly recommended that you watchlist it.
  • The project has several ongoing and developing activities, such as article quality assessment, peer review and a project-wide article collaboration, all of which you are welcome to take part in. We also have a unique program to improve our lower quality articles, Jumpaclass, so please consider signing up there.
  • If you have another language besides English, please consider adding yourself to our translation section, to help us improve our foreign LGBT topics.
  • If you're planning to stay, have a square in our quilt! You can put anything you want in it.

If you have any questions, feel free to ask on the talk page, and we will be happy to help you.

And once again - Welcome!

-- SatyrTN (talk | contribs) 16:32, 12 February 2007 (UTC)

Contents

[edit] Genetic level sex change, a possibility?

Originally from Talk:Transsexual, removed as it doesn't pertain to the article

Hi every1, i want to know something i guess that genetic medicine is not very advanced but, i was asking to myself something. Do u think that one of these days, a genetic sex reassignment theraphy can exist? i mean, do u think that scientists can develop a way to change all our genetical structure? that would be cool u know, because, even that it would be expensive, it would make of a transgender woman, a real woman (with possibilities of beign pregnant and that kind of stuff). My question is, if we use all our technology, do you think that kind of theraplhy would be a reality one of these days? —The preceding unsigned comment was added by 189.192.18.232 (talk • contribs) 01:51, 14 February 2007 UTC.

In reality, probably not for a LONG time.
Gene therapy has its limits, and does not necessarily mean the reconstruction of the body. It is certainly conceivable that therapy could be made to replace genetic material in a Y chromosome so that it acts as an X chromosome, however you need to remember that gene expression is not absolute; there is a phenomenon called penetrance to start with, and the hormonal and chemical status of a developing foetus has much to do with the end phenotype (how a person looks). Just look at the impact of Hormone replacement therapy - that is essentially turning on and off different gene expression in vivo. It would, however, be quite ironic; the VAST majority of a woman's second X chromasome is, in fact, inactive !!!! (See Barr body to see what it looks like in real life - btw, it's not all inactive, as women with only one X chromosome have Turner's syndrome and MOST women with two X chromosomes don not)
There are definitely ways to change our genetic structure; Epstein-Barr_Virus and HIV are both viruses that embed themselves into our DNA and change our genetic makeup forever. This is limited to certain cell lines, but the principle is there. (Any retrovirus will work by changing the DNA of the host cell permanently. --Puellanivis 08:07, 14 February 2007 (UTC))
In terms of giving a transsexual woman the ability to bear children, stem cell technologies are the way to go; You basically need a hollow organ with a blood supply (uterus) which has been achieved in the form of making a bladder; and you need to manage the early hormonal state of pregnancy (after a relatively short while, the placenta takes over the production of hormones). Of course, you still would need to produce an ovum from the transsexual woman, but there are already several technologies that could lead to that (such grabbing a spermatocyte during meiosis, and exchanging it's nucleus with that of a donated ova ovum; difficult, and with complications (such as the molar pregnancy)).
I would like to strongly point out, though, that even without this, Transsexual women identify as "real women" - just as some with intersex conditions identify as "real" women, despite similar (at least, post-GRS) anatomy.
Yes, I have researched this. I hope that it is in the future, but it is not likely in the current climate. I hope that helps.
P.S. if this is an issue you are going through, I recommend one of the many community sites and organizations set up to help transgendered and transsexual people - Cheers Lwollert 04:50, 14 February 2007 (UTC)
Please note that this is a talk page for improving the article itself, not for a general discussion of transsexualism. As noted above, many great online forums exist for discussing these issues. Thanks! Jokestress 05:04, 14 February 2007 (UTC)
From a wikipedia standpoint, such an action is unnecesary to be a "real woman", as mentioned above, Androgen insensitivty syndrome is where the karotype of an individual is XY, but their phenotype is female. There is a tendency to think that genetic distinction as XX would make us "real women", just like some people still believe that GRS will make them "real women". There's just no justification of that. Women who were raised as girls would still feel some separation from us as we were (most often) raised as boys, whether we shared exactly the same genetic material as them or not. Transsexual females will always be different from cisgender females, but that doesn't mean we're not "real", and being "real" isn't dependent upon how much or how little surgery/alteration we have. So basically, while this section may be an interesting tagent for some people while dreaming, it would provide no actual benefit to this article at all. Nothing short of changing history can make us identical to cisgender females. ... Oh, and sorry, but I just *have* to correct "Ova" to "Ovum", as the former is the plural of the latter, and the indefinite article "a/an" governs the singular. --Puellanivis 08:07, 14 February 2007 (UTC)
Along those same lines, I've heard/read a lot of comments from many transwomen who say "it takes more than a vagina to make a woman." Likewise, it takes more than a penis to make a man. Most cis-folk probably wouldn't agree with either statement (which is a large part of the problem), but I'd posit that it's extremely difficult to really understand trans-ness if you're not transgendered or transsexual. And even that isn't necessarily enough; as a transperson, sometimes I don't understand what it's all about either. <shrug> But as Jokestress says, this really isn't the place for this discussion. — Wwagner 16:41, 14 February 2007 (UTC)

ok, ok, thanks for that. i didn´t mean to offend any1 with my comment, it´s just that i am interested on that kind of technlogy and im also planning the sex change, ok? But anyways, thanks for clearing my doubts ppl. That´s why i luv wikipedia, u know, i find any kind of information i need, and i want to thank to all the ppl that has helped me on every doubt i have, really, thank u. :-)

No problem, but if you do identify as transsexual, I HIGHLY advise appropriate medical supervision from as early as possible; most clinics should understand if you are not prepared to transition immediately, but as pointed out above, non-cisgendered women and men have a LOT to work through - it's just not right for a girl to be brought up as a man (tongue-in-cheek, there). transsexuality, TS Roadmap, and Lynn Conway's Site are all useful resources, although the author of the last one is a little more controversial (at least according to TS Roadmap).
P.S. changed ova to ovum - thanks, I often muck that up.
P.P.S. to the unsigned poster we've been addressing, feel free to make an account and contribute!
P.P.P.S. As this discussion does not relate specifically to the article, it should be moved or deleted at some stage, probably soon. I'm happy to put it on my talk page for a bit, or are there other suggestions
Cheers, Lwollert 01:46, 15 February 2007 (UTC)
I was just thinking, that perhaps we could streamline it, get the important details and make it into a sort of sub-article that can then be placed on a person's User page. I kind of have something like that already on my user page with the "Hormone Therapy vs. Gilbert's Syndrome" entry.  :) --Puellanivis 02:38, 22 February 2007 (UTC)
Sounds interesting - I would certainly be interested in compiling the information - But it's mostly original research on my half so far, so do we run into wikipaedia rule issues? Or is it OKAY as a User's page?
BTW, In regards to your page, interestingly, I too have Gilbert's Syndrome, and am in the fairly rare (but thankfully not unique) position of being a final-year medical student (The medical training system over here (Australia) is quite different to over in America - basically, I know more general and much less specific knowledge than American graduates) as well as a Transwoman. I can say that the dose of estrogen you describe on your page is quite reasonable, and any higher you run into significant risks of Stroke, Deep Vein Thrombosis, and other similar medical conditions.
I can however, recommend adding progesterone in general for several reasons;
  1. Progesterone is a potent negative-feedback agent in the pituitary-gonadal axis; It helps block the production of testosterone quite effectively
  2. Because of the above, it may reduce the need for specific anti-androgens (such as spironolactone, which has significant "side effects" as well as complications - remember, its most common use is as a Diuretic.
  3. It allows the delivery of the hormones in a simple form - i.e. the Combined Oral Contraceptive Pill twice daily. An example is Ethinyoestrodiol 50mcg and Levornestregel 125 mcg.
As an alternative, look at Cyproterone Acetate, which although not approved by the FDA in america may still be available - It's a very potent anti-androgen
Don't forget, too, that ethinyloestradiol doesn't turn up on hormone assays - really the only useful test is Serum T - if that's in the female range, the hormones are doing their job. It takes time, patience, and a lot of frustration (from my limited experience, anyway.) I've also got a reference for a really good article from a year or two ago trying to get consensus on hormone treatment, I'll post it here when i get back from work tonight.
Cheers, Lwollert 00:29, 23 February 2007 (UTC)
I can´t believe this discussion moved so much people, whoa. Well, umm Lauren, i need to talk with you.check my youtube´s videos!!!!!!!!!!! just put raidentheninja on the search bar on youtube 23:31, 23 March 2007 (UTC)

[edit] LGBT WikiProject newsletter

[edit] DYK

Updated DYK query On 2 March 2007, Did you know? was updated with a fact from the article Classification of transsexuals, which you created or substantially expanded. If you know of another interesting fact from a recently created article, then please suggest it on the "Did you know?" talk page.

--Yomanganitalk 13:43, 2 March 2007 (UTC)

[edit] Jumpaclass intersexuality

Lwollert, I can't justify upgrading the article from a stub. My apologies. Dev920 (Have a nice day!) 15:40, 4 March 2007 (UTC)

Not a problem - ended up not being able to edit it enough
Cheers Lwollert 09:07, 6 March 2007 (UTC)

[edit] LGBTI

You said "Intersex communities and LGBT communities have worked together in the past". Have you got background information on this that you could help me find? It's been a few years since I had my old course materials close at hand. — coelacan — 10:14, 10 March 2007 (UTC)

Thanks, that's a start. — coelacan — 10:28, 10 March 2007 (UTC)

[edit] Lauren, i need help

Hi Lauren, my name is Lindsay, and i´d like to ask you for some help. I consider myself as a transsexual but, i have some doubts, and i feel really confused about what is going on, i don´t even know if i can make it. I told my mom about my wish of being a girl a few weeks ago, but she got very devastated. I don´t even know what to do, and im not sure if i can make it, my mother is trying to wash my brain with stupid ideas, when i know what i really want, i really need help lauren, pleasee check my youtube´s videos!!!!!!!!!!! just put raidentheninja on the search bar on youtube 23:31, 23 March 2007 (UTC)

[edit] thanks for the help, but i have something else to say

Hi, it´s me again, thanks for the help, i just have one more question, how much money do you think i would need to have a complete reassignment? im talking about hormonal treatment, surgeries, breast augmentation, everyhting. and i have another question, what is the electrolysis for? isn´t supposed to be that the laser epilation is for that? what methods are the most used in the hair removal process? thanks for your help, and i hope i can survive to this, because i really want to make this dream to come true xoxo take care lauren, and hanks :-) check my youtube´s videos!!!!!!!!!!! just put raidentheninja on the search bar on youtube 00:56, 25 March 2007 (UTC)

[edit] thanks lauren

Thanks for all the things that you have told me, i really aprecciate it, i´d also like to say that i liked the way you talked to me. so i´d like to be your friend, because im gonna need some real support for this (at least someone who can listen ot me) I leave you my MSN and yahoo I hope we can talk again, take care, and once again, thanks for everything

Lindsay

check my youtube´s videos!!!!!!!!!!! just put raidentheninja on the search bar on youtube 01:22, 25 March 2007 (UTC)

[edit] LGBT WikiProject Newsletter

[edit] LGBT WikiProject newsletter

SatyrBot 05:13, 3 April 2007 (UTC)

Retrieved from "http://en.wikipedia.org../../../l/w/o/User_talk%7ELwollert_ac30.html"