Lufenuron
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| Lufenuron | |
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| IUPAC name | 1-[2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea |
| Other names | N-[ [ [2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino]carbonyl]-2,6-difluorobenzamide Fluphenacur U.S. EPA PC Code: 118205 |
| Identifiers | |
| CAS number | [] |
| SMILES | O=C(NC(C2=C(F)C=CC=C2F)=O)NC1=CC(Cl)=C(OC(F)(F)C(C(F)(F)F)F)C=C1Cl |
| Properties | |
| Molecular formula | C17H8Cl2F8N2O3 |
| Molar mass | 511.15 g/mol |
| Melting point |
174 °C, 447 K, 345 °F |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Lufenuron is the active ingredient in the veterinary flea control medicine, Program, and the veterinary coformulation flea control, heartworm prevention, and anthelmintic medicine, Sentinel.
Lufenuron is stored in the animal's body fat and transferred to adult fleas through their bite. Adult fleas transfer it to their eggs by its presence in the mother flea's blood, or by the larva feeding on pre-digested blood.
Lufenuron, a benzoylurea pesticide, inhibits the production of chitin in larval fleas. Without chitin, a larval flea will never develop an exoskeleton. Attacking the ability to create chitin may make lufenuron an effective remedy against fungal infections, such as ringworm (a dermatophyte infection and not a worm at all).
It has no known toxic effects at any dosage on humans or other animals in the environment that do not depend on chitin, though the orally-administered pills can sometimes cause an upset stomach with acid reflux.
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