Lipopolysaccharide-Binding Protein

From Wikipedia, the free encyclopedia

Lipopolysaccharide-Binding Protein (LBP) is a soluble protein that binds to bacterial lipopolysaccharide (or LPS) to elicit immune responses by presenting the LPS to important cell surface pattern recognition receptors called CD14 and TLR4.[1]


[edit] References

  1. ^ Muta and Takeshige. Essential roles of CD14 and lipopolysaccharide-binding protein for activation of toll-like receptor (TLR)2 as well as TLR4: Reconstitution of TLR2- and TLR4-activation by distinguishable ligands in LPS preparations. Eur. J. Biochem. 268, 4580-4589 (2001)