Limb bud
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In embryology, the limb bud is a structure formed by the developing limb, derived from lateral plate mesoderm[citation needed]. It is intimately related with the apical ectodermal ridge, which secretes factors inducing the initial differentiation of the limb bud. In turn, the mesodermal tissue of the limb bud secretes factors sustaining the development of the AER.
| Mammalian development of embryo and development of fetus (some dates are approximate - see Carnegie stages) |
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| Week 1: Zygote - Morula - Blastula/Blastomere/Blastosphere - Archenteron/Primitive streak - Blastopore - Allantois - Trophoblast (Cytotrophoblast - Syncytiotrophoblast - Gestational sac)
Week 2: Yolk sac - Vitelline duct - Bilaminar disc Week 3: Hensen's node - Gastrula/Gastrulation - Trilaminar embryo Branchial arch (1st) - Branchial pouch - Meckel's cartilage - Somite/Somitomere - Sclerotome - Myotome - Germ layer (Ectoderm, Endoderm, Mesoderm, Chordamesoderm, Paraxial mesoderm, Intermediate mesoderm, Lateral plate mesoderm, Splanchnopleure, Somatopleure) Histogenesis and Organogenesis Uterine support: Placenta - Umbilical cord (Umbilical artery, Umbilical vein, Wharton's jelly) - Amniotic sac (Amnion, Chorion) Limb development: Limb bud - Apical Ectodermal Ridge/AER |
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