Talk:Ligand (biochemistry)

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Contents 1 Ligand merger, NO 2 Merge notice 2.1 Ligand 2.2 Ligand2 3 ligand binding affinity 4 Disambiguation 5 Ya

[edit] Ligand merger, NO

I see significant difference. The bio definition would have been NO help in answering my chemistry student's question. The chem definition was precisely what I needed. 68.114.63.121 20:09, 5 April 2006 (UTC)Chem Teacher

[edit] Merge notice

I do not quite see the difference between the definition here and the definition at ligand, so I suggest we merge these two articles. / Habj 01:50, 8 November 2005 (UTC)

agreed (141.211.222.165) (copied from Talk:Ligand by User:Walkerma

[edit] Ligand

I see a big difference, in chemistry ligand has quite a different meaning than in biochemistry, and the explanation that is given here starts to show that difference. User:Kirklucy

I strongly disagree with this proposed merge for two reasons.

1. A ligand in inorganic chemistry is completely different from a biochemical ligand. For example a biochemical ligand is usually held in place by weak intermolecular attractions, whereas a chemical ligand is usually bound quite strongly.
2. Aside from this, each concept is important enough in its own field to warrant having its own article. Walkerma 02:53, 17 December 2005 (UTC)

Also in the edit history for this article, is a comment by User:Melianis, "this one needs way more work, but not merge".

Hi i'm just a science reader but i also disagree with this merge: In biology, a ligand is an extracellular substance that binds to receptors.

In chemistry, a ligand is an atom, ion or functional group that donates its electrons through a coordinate covalent bond to one or more central atoms or ions, usually metals. An array of such ligands around a center is termed a complex.

The two concepts, in chemistry and biochemistry, should remain separate. User:Ceyockey 19:19, 28 December 2005 (UTC)

While the two concepts are different, it might help to mention briefly(with a link) in each article, the other concept, so that a person looking for general information has the option of using either or both.

Agreed, the concepts are related, but not the same. 71.96.132.182 22:28, 8 January 2006 (UTC)

I personally would like them separate. This is the information I was looking for, not the other.--Dan 02:00, 21 January 2006 (UTC)

• I also disagree with the merge and I think the majority also disagrees. Therefore the merge notices should be removed V8rik 22:01, 18 April 2006 (UTC)

[edit] Ligand2

I think the biological definition should be moved to the biochemical ligand page since it is just a simplified version of the biochemical definition. What is the reason for having the biological definition on the chemistry page and the biochemical definition separate?

[edit] ligand binding affinity

I am going to add another figure to better illustrate K_d and binding affinity. --JWSchmidt 04:04, 24 January 2006 (UTC)

[edit] Disambiguation

I have created the page ligand (disambiguation) and added the otheruses template to ligand and ligand (biochemistry). When checking what links to ligand (these links), I feel that many of them should actually point to ligand (biochemistry). Could you help me sorting these out? --Dirk Beetstra 10:10, 3 June 2006 (UTC)

[edit] Ya

Is "ya" a misspelling in "resulting in altered behavior of an ya associated ion channel or enzyme"? If so, can someone with more knowledge than I correct this? David 00:52, 8 January 2007 (UTC)