Langhans giant cell

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Langhans giant cells are large cells found in granulomatous conditions. They are formed by the fusion of epithelioid cells (macrophages), and contain nuclei arranged in a horseshoe-shaped pattern in the cell periphery. Their presence could indicate tuberculosis.

They should not be confused with Langerhans cell. According to MeSH, Langhans giant cells are macrophages, but Langerhans cells are not.

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Blood
Plasma Hematopoietic stem cells - Red blood cells (Reticulocyte, Normoblast) - White blood cells
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Myeloid Granulocytes (Neutrophil, Eosinophil, Basophil) - Mast cell precursors
Dendritic cells (Langerhans cells) - Monocytes/Macrophages (Histiocytes, Kupffer cells, Langhans giant cells, Microglia, Osteoclasts)
Megakaryoblast - Megakaryocyte - Platelets
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