Lamin A

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Lamin A is one of the intermediate filament proteins that weave together to form a shell called the nuclear lamina which lines the inner surface of the nucleus of every eukaryotic cell. Lamin A and its closely related variant, Lamin C, are both derived from the same gene by Alternative splicing of a shared pre-mRNA transcript.

The Lamin A gene is located on chromosome 1, and mutations in its sequence have been shown to cause diseases such as Progeria and Muscular Dystrophy (also see: laminopathies).

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Proteins of the cytoskeleton

Microfilaments: Actins - Myosins - Actin-binding proteins

Intermediate filaments: type 1 and 2 Cytokeratin (type I, type II)
type 3 Desmin, GFAP, Peripherin, Vimentin
type 4 Internexin, Nestin, Neurofilament
type 5 Lamin (A, B)

Microtubules: Dyneins - Kinesins - MAPs (Tau protein) - Tubulins

Prokaryotic cytoskeleton: Crescentin - FtsZ - MreB

Other: Major Sperm Proteins


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