L-type calcium channel
From Wikipedia, the free encyclopedia
The L-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit is the one that determines most of the channel's properties.
L-type calcium channel blockers are used as antiarrhythmics or antihypertensives, depending on whether the drugs has higher affinity to the heart (like verapamil) or to the vessels (nifedipine).
L-type channels are selectively blocked by dihydropyridines.
Contents |
[edit] See also
[edit] Genes
[edit] See also
[edit] External links
Stretch-activated ion channel - Ligand-gated ion channel - Voltage-gated ion channel
Ca: Voltage-dependent calcium channel (L-type/CACNA1C, N-type, P-type, Q-type, R-type, T-type) - Inositol triphosphate receptor - Ryanodine receptor - Cation channels of sperm
Na: Sodium channel: SCN4A - SCN5A - SCN9A - Epithelial sodium channel
K: Potassium channel: Voltage-gated (KvLQT1, HERG, Shaker gene, KCNE1) - Calcium-activated (BK channel, SK channel) - Inward-rectifier (ROMK, KCNJ2) - Tandem pore domain/Resting ion channel
Cl: Chloride channel: Cystic fibrosis transmembrane conductance regulator
Transient receptor potential (TRPV6) - Cyclic nucleotide-gated ion channel - Two-pore channel
