Keratin 6A

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keratin 6A
Identifiers
Symbol KRT6A
HUGO 6443
Entrez 3853
OMIM 148041
RefSeq NM_005554
UniProt P02538
Other data
Locus Chr. 12 q12-q21

Keratin 6A is a type II cytokeratin, one of several isoforms of keratin 6. It is found with keratin 16 and/or keratin 17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This keratin 6 isoform is the most abundant one. Mutations in these genes expressing this protein have been associated with pachyonychia congenita.

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Protein: fibrous proteins

Collagen (Type-I, Type-II, Type-III, Type-IV, Type-XVIII) - Elastin - Cytoskeletal

Keratin: Cyto- (Type I, Type II), type I ( 10, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21), type II ( 1, 2A, 3, 4, 5, 6A, 7, 8, 9), Hair (Type I, Type II), Beta


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