Keratin 18

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keratin 18
Identifiers
Symbol KRT18
HUGO 6430
Entrez 3875
OMIM 148070
RefSeq NM_199187
UniProt P05783
Other data
Locus Chr. 12 q13

Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.


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Protein: fibrous proteins

Collagen (Type-I, Type-II, Type-III, Type-IV, Type-XVIII) - Elastin - Cytoskeletal

Keratin: Cyto- (Type I, Type II), type I ( 10, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21), type II ( 1, 2A, 3, 4, 5, 6A, 7, 8, 9), Hair (Type I, Type II), Beta

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