Keratin 1

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keratin 1
Identifiers
Symbol KRT1 EHK1
HUGO 6412
Entrez 3848
OMIM 139350
RefSeq NM_006121
UniProt P04264
Other data
Locus Chr. 12 q11-q13

Keratin 1 is a member of the keratin family. It is specifically expressed in the spinous and granular layers of the epidermis with family member keratin 10. Mutations in this gene have been associated with the variants of bullous congenital ichthyosiform erythroderma in which the palms and soles of the feet are affected.

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Protein: fibrous proteins

Collagen (Type-I, Type-II, Type-III, Type-IV, Type-XVIII) - Elastin - Cytoskeletal

Keratin: Cyto- (Type I, Type II), type I ( 10, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21), type II ( 1, 2A, 3, 4, 5, 6A, 7, 8, 9), Hair (Type I, Type II), Beta

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