ITK (gene)

From Wikipedia, the free encyclopedia

IL2-inducible T-cell kinase
Image source: 1SNX
Available structures: 1SNX, 2ETZ, 2EU0, 1LUK, 1LUM, 1LUN, 1LUI, 1AWJ, 1SNU, 1SM2
Identifiers
Symbol(s)	ITK EMT; LYK; PSCTK2; MGC126257; MGC126258
External IDs	OMIM: 186973 MGI: 96621 Homologene: 4051
Function
Gene Ontology	• Nucleotide binding • Non-membrane spanning protein tyrosine kinase activity • ATP binding • Protein amino acid phosphorylation • Cellular defense response • Intracellular signaling cascade • Zinc ion binding • Kinase activity • Transferase activity • Metal ion binding
Orthologs
	Human	Mouse
Entrez	3702	16428
Ensembl	ENSG00000113263	ENSMUSG00000020395
Uniprot	Q08881	Q03526
Refseq	NM_005546 (mRNA) NP_005537 (protein)	NM_010583 (mRNA) NP_034713 (protein)
Location	Chr5: 156.54 - 156.62 Mb	Chr11: 46.28 - 46.35 Mb
Gene Expression	211339_s_at	103028_at 1417171_at 1452518_a_at 1457120_at
	Compare all orthologs