IPEX
From Wikipedia, the free encyclopedia
| OMIM | 304790 |
|---|---|
| DiseasesDB | 33417 |
IPEX stands for immunodysregulation polyendocrinopathy enteropathy X-linked syndrome and it is a disease linked to the dysfunction of the transcriptional activator FoxP3.
It leads to the dysfunction of regulatory T-cells and the subsequent autoimmunity.
This autoimmunity is called IPEX and it is the attack from the body's own immune system against the body's own tissues and organs.
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