Intracellular receptor

From Wikipedia, the free encyclopedia

Intracellular receptors are receptors located inside the cell rather than on its cell membrane. Examples are the class of nuclear receptors located in the cell nucleus and the IP₃ receptor located on the endoplasmic reticulum. The ligands that bind to them are usually intracellular second messengers like inositol trisphosphate (IP₃) and extracellular lipophilic hormones like steroid hormones.

Contents 1 Members 1.1 Transcription factors 1.2 Various 2 See also 3 External links

[edit] Members

[edit] Transcription factors

• Steroid hormone receptor:
  • Sex hormone receptors (sex hormones)
    • Estrogen receptor (α and β)
    • Androgen receptor (one type)
  • Vitamin D receptor (vitamin D, one type)
  • Glucocorticoid receptor (glucocorticoids, one type)
  • Mineralocorticoid receptor (mineralocorticoids, one type)
• Thyroid hormone receptor (α and β)
• Retinoic acid receptor (vitamin A and related compounds);
• Peroxisome proliferator-activated receptors (PPARs, α, γ and δ)
• Retinoid X receptor
• Farnesoid X receptor
• Liver X receptor
• Pregnane X receptor
• Constitutive androstane receptor

[edit] Various

• Sigma1 (neurosteroids))
• IP₃ receptor (inositol triphosphate, IP₃)

[edit] See also

• Receptor
• Steroid hormone

[edit] External links

• Nuclear Receptor journal homepage
• Nuclear receptor resource at Georgetown University
• Nuclear receptor signalling atlas (NURSA, open-access journal)