Intimin
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Intimin is a virulence factor (adhesin) of EPEC (e.g. E. coli O127:H6) and EHEC (e.g. E. coli O157:H7) E. coli strains. It is an attaching and effacing (A/E) protein which with other virulence factors is responsible for enteropathogenic and enterohaemorrhagic diarrhoea.
Intimin along with its host cell receptor - Tir (Translocated intimin receptor) are secreted from E. coli by a Type three secretion system.
[edit] External link
- [1] UniProt/Swiss-Prot page on Intimin
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