Interleukin 28

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Interleukin 28A
Identifiers
Symbol IL28A , IFNL2
HUGO 18364
Entrez 282616
OMIM 607401
RefSeq NM_172138
UniProt Q8IZJ0
Other data
Locus Chr. 19 q13.13
Interleukin 28B
Identifiers
Symbol IL28B , IFNL3
HUGO 18365
Entrez 282617
OMIM 607402
RefSeq NM_172139
UniProt Q8IZI9
Other data
Locus Chr. 19 q13.13

Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses.[1] IL-28A and IL-28B belong to the type I interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29.

IL-28 genes are located near IL-29 on chromosome 19 in humans.

[edit] References

  1. ^ D. Kempuraj et al., Interleukin-28 and 29 (IL-28 and IL-29): new cytokines with anti-viral activities. International Journal of Immunopathology and Pharmacology, 2004, Volume 17, pages 103-106.