In vitro toxicology
From Wikipedia, the free encyclopedia
In vitro toxicology is the scientific analysis of the effects of toxic chemical substances on cultured bacteria or mammalian cells. In vitro (literally 'in glass') testing methods are employed primarily to identify potentially hazardous chemicals and/or to confirm the lack of certain toxic properties in the early stages of the development of potentially useful new substances such as therapeutic drugs, agricultural chemicals and direct food additives. Most toxicologists believe that in vitro toxicity testing methods can be a useful, time and cost-effective supplement to toxicology studies in living animals (which are termed in vivo or "in life" methods). However, it is generally accepted that the available in vitro tests are not presently adequate to entirely replace animal toxicology tests.
[edit] External links
- Mouse Lymphoma Assay Calculations
- Introduction to Genetic Toxicology
- Alt Web
- The Johns Hopkins Center for Alternatives to Animal Testing (CAAT)
- 3-D, Human Cell-Derived TISSUES for Tox. Testing - MatTek Corp.
- In Vitro Toxicology Specialty Section - Society of Toxicology
- In Vitro Phototoxicity Testing