Ichthyosis
From Wikipedia, the free encyclopedia
Ichthyosis is a family of dermatological conditions seen in humans and domestic animals. Its literal translation is "fish skin", since people or animals with ichthyosis have scaly skin which can vaguely resemble the scales of a fish. The conditions are caused by genetic abnormalities.
The term ichthyosis is sometimes used to mean the specific condition ichthyosis vulgaris.
Ichthyosis was formerly referred to as "pseudo-leprosy," as it can produce an appearance superficially similar to that of leprosy.
Contents |
[edit] Types
Some types of ichthyosis include:
- Ichthyosis bullosa of Siemens
- Ichthyosis vulgaris
- Ichthyosis lamellaris
- X-linked ichthyosis
- Epidermolytic hyperkeratosis
- Ichthyosis acquisita
- Harlequin type ichthyosis
- Netherton's syndrome
- Sjögren-Larsson syndrome
- Ichthyosis Erythrokeratoderma variabolis
[edit] Ichthyosis in domestic dogs
Ichthyosis of varying severity is seen as a hereditary disorder in some breeds of domestic dogs. The best characterized forms are found in Golden retrievers, American bulldogs, Jack Russell terriers and Cairn terriers.
[edit] Diagnosis
A physician (or veterinarian) often can diagnose ichthyosis by looking at the skin. A family history is also very useful. In some cases, a skin biopsy will be done to help to confirm the diagnosis. In a biopsy, a small piece of skin is removed and examined under a microscope. In rare instances, genetic testing may be helpful in making a diagnosis. Ichthyosis is not more or less common in any ethnic group. As of now, there is no way to prevent ichthyosis.
[edit] Treatments
Treatments for ichthyosis often take the form of topical application of creams and oils, in an attempt to hydrate the skin. Retinoids are also used for some conditions. Exposure to sunlight may improve or worsen the condition.
There can be ocular manifestations of ichthyosis, such corneal and ocular surface diseases. Vascularizing keratitis, which is more commonly found in congenital keratitis-ichythosis-deafness (KID) may worsen with isotretinoin therapy. Ectropion, if it occurs, can be treated surgically after skin hydration.
See also: psoriasis
