Ibutilide

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Ibutilide
Systematic (IUPAC) name
N-[4-[4-(ethyl-heptyl-amino)- 1-hydroxy-butyl]phenyl] methanesulfonamide
Identifiers
CAS number	122647-32-9
ATC code	C01BD05
PubChem	60753
DrugBank	APRD01025
Chemical data
Formula	C20H36N2O3S
Mol. mass	384.578 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	40%
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Ibutilide (ibutilide fumarate) is a class III antiarrhythmic agent. It is associated with an extremely high rate of adverse effects, including torsades de pointes. It is not licensed for use in the UK, but is still available in the U.S.

v • d • e Antiarrhythmic agents (C01B)
class Ia	Ajmaline, Disopyramide, Prajmaline, Procainamide, Quinidine, Sparteine
class Ib	Aprindine, Lidocaine, Mexiletine, Tocainide
class Ic	Encainide, Flecainide, Lorcainide, Moricizine, Propafenone
class II	Propranolol, Metoprolol, Nadolol, Atenolol, Acebutolol, Pindolol see Beta blockers (C07)
class III	Amiodarone, Bretylium tosylate, Bunaftine, Dofetilide, Ibutilide, Sotalol
class IV	Verapamil, Diltiazem see Calcium channel blockers (C08)
class V	Adenosine, Atropine, Digoxin