Talk:Hydrophobe

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rated top as high school/SAT biology content - tameeria 14:46, 17 February 2007 (UTC)

This article needs to be expanded with a section on hydrophobicity in biochemistry, e.g. role in lipid bilayer formation, protein folding etc. - tameeria 18:31, 18 February 2007 (UTC)

molecules that ??prefer?? non polar molecules! Poor anthropomorphic description imho. Bad science in fact. Should be corrected. Anyone?


Hydrophile water lover. The opposite of a water lover is a hydrophobe, a person suffering hydrophobia. Your discussion of these and related words is focussing on the chemical meaning which are correct. However if your explanation of hydrophobia is correct, then my interpretation of hydrophile, a person who loves the water, is also correct. Bibliophile a person who loves books. Logophile a person who loves words, which is what I am and no doubt you are too. I have written a nautical dictionary and I have put the following in my dictionary Hydrophile a lover of water and aquatic activities. I accept that the later may be a slight amplification. www.xtreme.net/mewburn mewburn@xtreme.net

Cheers Gray Graham Mewburn

Contents

[edit] Pictures

It would be nice to get some pictures like these: [1] [2] [3]Omegatron 18:54, 15 April 2006 (UTC)

[edit] Lipophilic redirects to hydrophobic

"Hydrophobic is often used interchangeably with "lipophilic". However, the two terms are not synonymous." In light of this, perhaps lipophilic shouldn't redirect to hydrophilic ;) I'm still unclear on the difference between lipophilia and hydrophilia dikaiopolis 03:47, 12 September 2006 (UTC)


[edit] Anthropomorphic

Added an anthropomorphism section. Not brave enough to edit the existing "Chemical background" but some of it reads very wrongly.

e.g. "Water is electrically polarized, and is able to form hydrogen bonds internally, which gives it many of its unique physical properties. But, since hydrophobes are not electrically polarised, and because they are unable to form hydrogen bonds, water repels hydrophobes, in favour of bonding with itself."

This sounds pretty much like drivel to me. There are hydrogen bonds and Van-der-Waals and interactions between.

Maybe its been left because its peripheral to proper chemistry. Walworth 00:40, 1 December 2006 (UTC)

[edit] For chemicals there are substructure based prediction methods

Substructure based prediction methods are called group contribution methods and a couple of fragments and SMARTS patterns for creating an example can be found here. A potential reference is Corwin Hansch, Alka Kurup, Rajni Garg, Hua Gao, Chem-Bioinformatics and QSAR: A Review of QSAR Lacking Positive Hydrophobic Terms, Chem. Rev. 2001, 101, 619-672. JKW 03:49, 14 December 2006 (UTC)