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[edit] Single-season Batting Leaders
- Batting Average: Jeff Bagwell (.367, 1994)
- On-base percentage: Jeff Bagwell (.454, 1999)
- Slugging Percentage: Jeff Bagwell (.750, 1994)
- OPS: Jeff Bagwell (1.201, 1994)
- At Bats: Enos Cabell (660, 1978)
- Runs: Jeff Bagwell (152, 2000)
- Hits: Craig Biggio (210, 1998)
- Total Bases: Jeff Bagwell (363, 2000)
- Doubles: Craig Biggio (56, 1999)
- Triples: Roger Metzger (14, 1973)
- Home Runs: Jeff Bagwell (47, 2000)
- Runs Batted In: Lance Berkman (136, 2006)
- Walks: Jeff Bagwell (149, 1999)
- Strikeouts: Lee May (145, 1972)
- Stolen Bases: Gerald Young (65, 1988)
- Singles: Sonny Jackson (160, 1966)
- Extra-Base Hits: Lance Berkman (94, 2001)
- Times on Base: Jeff Bagwell (331, 1999)
- Hit By Pitch: Craig Biggio (34, 1997)
- Sacrifice Hits: Craig Reynolds (34, 1979)
- Intentional Walks: Jeff Bagwell (27, 1997)
- Grounded into Double Plays: Brad Ausmus (30, 2002)
- At Bats per Strikeout: Bob Lillis (40.8 in 1965)
- At Bats per Home Run: Jeff Bagwell (10.3, 1994)
[edit] Single-season Pitching Leaders
- ERA: Roger Clemens (1.87, 2005)
- Wins: Mike Hampton (22, 1999)
- Won-Loss %: Mike Hampton (.846, 1999)
- WHIP: Mike Scott (.923, 1986)
- Hits Allowed per 9 Innings Pitched: Mike Scott (5.95, 1986)
- Walks per 9 Innings Pitched: Jose Lima (1.23, 1998)
- Strikeouts per 9 Innings Pitched: Nolan Ryan (11.48, 1987)
- Games: Octavio Dotel (83, 2002)
- Saves: Billy Wagner (44, 2003)
- Innings: Larry Dierker (305 1/3, 1969)
- Strikeouts: J.R. Richard (313, 1979)
- Games Started: Jerry Reuss (40, 1973)
- Complete Games: Larry Dierker (20, 1969)
- Shutouts: Dave Roberts (6, 1973)
- Home Runs Allowed: Jose Lima (48, 2000)
- Walks Allowed: J.R. Richard (151, 1976)
- Hits Allowed: Jerry Reuss (271, 1973)
- Strikeout to Walk: Shane Reynolds (5.32, 1999)
- Losses: Turk Farrell (20, 1962)
- Earned Runs Allowed: Jose Lima (145, 2000)
- Wild Pitches: Joe Niekro (21, 1985)
- Batters Faced: J.R. Richard (1,218, 1976)
- Games Finished: Doug Jones (70, 1992)