Hot 100 number-one hits of 1968 (USA)
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These are the Billboard magazine Hot 100 number one hits of 1968.
| Issue Date | Song | Artist |
| January 6 | Hello, Goodbye | The Beatles |
| January 13 | Hello, Goodbye | The Beatles |
| January 20 | Judy in Disguise (with Glasses) | John Fred and His Playboy Band |
| January 27 | Judy in Disguise (with Glasses) | John Fred and His Playboy Band |
| February 3 | Green Tambourine | The Lemon Pipers |
| February 10 | Love is Blue | Paul Mauriat |
| February 17 | Love is Blue | Paul Mauriat |
| February 24 | Love is Blue | Paul Mauriat |
| March 2 | Love is Blue | Paul Mauriat |
| March 9 | Love is Blue | Paul Mauriat |
| March 16 | (Sittin' on) the Dock of the Bay | Otis Redding |
| March 23 | (Sittin' on) the Dock of the Bay | Otis Redding |
| March 30 | (Sittin' on) the Dock of the Bay | Otis Redding |
| April 6 | (Sittin' on) the Dock of the Bay | Otis Redding |
| April 13 | Honey | Bobby Goldsboro |
| April 20 | Honey | Bobby Goldsboro |
| April 27 | Honey | Bobby Goldsboro |
| May 4 | Honey | Bobby Goldsboro |
| May 11 | Honey | Bobby Goldsboro |
| May 18 | Tighten Up | Archie Bell & the Drells |
| May 25 | Tighten Up | Archie Bell & the Drells |
| June 1 | Mrs. Robinson | Simon and Garfunkel |
| June 8 | Mrs. Robinson | Simon and Garfunkel |
| June 15 | Mrs. Robinson | Simon and Garfunkel |
| June 22 | This Guy's in Love with You | Herb Alpert |
| June 29 | This Guy's in Love with You | Herb Alpert |
| July 6 | This Guy's in Love with You | Herb Alpert |
| July 13 | This Guy's in Love with You | Herb Alpert |
| July 20 | Grazing in the Grass | Hugh Masekela |
| July 27 | Grazing in the Grass | Hugh Masekela |
| August 3 | Hello, I Love You | The Doors |
| August 10 | Hello, I Love You | The Doors |
| August 17 | People Got to Be Free | The Rascals |
| August 24 | People Got to Be Free | The Rascals |
| August 31 | People Got to Be Free | The Rascals |
| September 7 | People Got to Be Free | The Rascals |
| September 14 | People Got to Be Free | The Rascals |
| September 21 | Harper Valley PTA | Jeannie C. Riley |
| September 28 | Hey Jude | The Beatles |
| October 5 | Hey Jude | The Beatles |
| October 12 | Hey Jude | The Beatles |
| October 19 | Hey Jude | The Beatles |
| October 26 | Hey Jude | The Beatles |
| November 2 | Hey Jude | The Beatles |
| November 9 | Hey Jude | The Beatles |
| November 16 | Hey Jude | The Beatles |
| November 23 | Hey Jude | The Beatles |
| November 30 | Love Child | Diana Ross & the Supremes |
| December 7 | Love Child | Diana Ross & the Supremes |
| December 14 | I Heard It through the Grapevine | Marvin Gaye |
| December 21 | I Heard It through the Grapevine | Marvin Gaye |
| December 28 | I Heard It through the Grapevine | Marvin Gaye |
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