Hot 100 number-one hits of 1961 (USA)
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These are the Billboard magazine Hot 100 number one hits of 1961.
| Issue Date | Song | Artist |
| January 2 | Are You Lonesome Tonight? | Elvis Presley |
| January 9 | Wonderland by Night | Bert Kaempfert |
| January 16 | Wonderland by Night | Bert Kaempfert |
| January 23 | Wonderland by Night | Bert Kaempfert |
| January 30 | Will You Love Me Tomorrow | The Shirelles |
| February 6 | Will You Love Me Tomorrow | The Shirelles |
| February 13 | Calcutta | Lawrence Welk |
| February 20 | Calcutta | Lawrence Welk |
| February 27 | Pony Time | Chubby Checker |
| March 6 | Pony Time | Chubby Checker |
| March 13 | Pony Time | Chubby Checker |
| March 20 | Surrender | Elvis Presley |
| March 27 | Surrender | Elvis Presley |
| April 3 | Blue Moon | The Marcels |
| April 10 | Blue Moon | The Marcels |
| April 17 | Blue Moon | The Marcels |
| April 24 | Runaway | Del Shannon |
| May 1 | Runaway | Del Shannon |
| May 8 | Runaway | Del Shannon |
| May 15 | Runaway | Del Shannon |
| May 22 | Mother-in-Law | Ernie K-Doe |
| May 29 | Travelin' Man | Ricky Nelson |
| June 5 | Running Scared | Roy Orbison |
| June 12 | Travelin' Man | Ricky Nelson |
| June 19 | Moody River | Pat Boone |
| June 26 | Quarter to Three | Gary U.S. Bonds |
| July 3 | Quarter to Three | Gary U.S. Bonds |
| July 10 | Tossin' and Turnin' | Bobby Lewis |
| July 17 | Tossin' and Turnin' | Bobby Lewis |
| July 24 | Tossin' and Turnin' | Bobby Lewis |
| July 31 | Tossin' and Turnin' | Bobby Lewis |
| August 7 | Tossin' and Turnin' | Bobby Lewis |
| August 14 | Tossin' and Turnin' | Bobby Lewis |
| August 21 | Tossin' and Turnin' | Bobby Lewis |
| August 28 | Wooden Heart (Muss I Denn) | Joe Dowell |
| September 4 | Michael | The Highwaymen |
| September 11 | Michael | The Highwaymen |
| September 18 | Take Good Care of My Baby | Bobby Vee |
| September 25 | Take Good Care of My Baby | Bobby Vee |
| October 2 | Take Good Care of My Baby | Bobby Vee |
| October 9 | Hit the Road Jack | Ray Charles |
| October 16 | Hit the Road Jack | Ray Charles |
| October 23 | Runaround Sue | Dion |
| October 30 | Runaround Sue | Dion |
| November 6 | Big Bad John | Jimmy Dean |
| November 13 | Big Bad John | Jimmy Dean |
| November 20 | Big Bad John | Jimmy Dean |
| November 27 | Big Bad John | Jimmy Dean |
| December 4 | Big Bad John | Jimmy Dean |
| December 11 | Please Mr. Postman | The Marvelettes |
| December 18 | The Lion Sleeps Tonight | The Tokens |
| December 25 | The Lion Sleeps Tonight | The Tokens |
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1940 | 1941 | 1942 | 1943 | 1944 | 1945 | 1946 | 1947 | 1948 | 1949 |
