Talk:Histamine

From Wikipedia, the free encyclopedia

Chemicals WikiProject Histamine is within the scope of WikiProject Chemicals, a daughter project of WikiProject Chemistry, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project.
Core This is a core article in the WikiProject Chemicals worklist
Start This article has been rated as start-Class on the quality scale.
Mid This article has been rated as mid-importance on the importance scale.

Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need.

Contents

[edit] sources

Where in the name of all the is holy did this information come from?! There is not a single source cited in this entire article. I have flagged this and will be looking for sources. It would be nice if some emails were sent out to some professors requesting some help with a rewrite. Foolishben 18:32, 27 November 2006 (UTC)

[edit] nomenclature

The chemical structure is wrong. The hydrogen atoms should be shown on the ethylamine nitrogen atom and one of the ring nitrogen atoms.

From Gizzy:- Correct ... Well Done!!!

[edit] Imbalances

I can find absolutely no reference to histapenia or histadelia and the effects listed in any reputable medical sourcebook or database. None of the pharmacists I've worked with have heard of it, either, though I haven't spoken with my physician about it. What are the primary sources for this information? Archmage Brian 14:45, 9 October 2006 (UTC)

These words were coined in the early 1970s by Carl C. Pfeiffer, the director of the Brain Bio Center in Skillman (just north of Princeton), NJ (He'd been chief pharmacologist of the Navy for 20 years, and was both an MD and a PhD; his wife was also his colleague.) to indicate two of several postulated alternative mechanisms at work in "the schizophrenias". He wrote about four or five books for the general public and (I suspect) many scholarly papers. In particular, I recall them being discussed in _Mental and Elemental Nutrients_ and _Zinc and Other Micronutrients_ (?). Somebody else will have to look into this, though, since it's been many years since I read them. There is now another Brain Bio Center, located in Colorado, I think. Like Pfeiffer, they're continuing the work of the orthomolecular psychiatry school, founded by Abram Hoffer and Humphrey Osmond. If I recall correctly, histapenia is treated mainly with niacin and histadelia with pyridoxine, among numerous supporting nutrients and pharmaceuticals. --Marshall Price of Miami-- D021317c 12:09, 1 December 2006 (UTC)

Incidentally, the words I was referring to above are "histadelia" and "histapenia". Pfeiffer is in the hall of fame at http://www.orthomolecular.org/history/index.shtml D021317c 22:07, 27 January 2007 (UTC)

[edit] H substance

What is H substance? The article says it is "held to be similar to histamine; or possibly to be histamine itself" - is this a misconception or a mistake? In other articles it appears to be a synonym for Substance H, which redirects to Hh antigen system. --apers0n 09:16, 7 November 2006 (UTC)