Talk:HERG

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This sounds fake to me. Ether-a-go-go? Anyone care to explain this ridiculous-sounding name? —Keenan Pepper 10:00, 11 August 2005 (UTC)

No, its quite factual. The hERG channel was identified in Drosophila flies and named so because when they were anaesthetised with ether, their legs started shaking.

bignoter 11:20, August 16, 2005 (UTC)

D. melanogaster gene ether a go-go , abbreviated as eag, encodes a product with voltage-gated potassium channel activity involved in courtship behavior. Mutants shake their legs under ether anesthesia. HERG channel, or KCNH2, is encoded by the eag-related gene, they share some characteristic but are two distinct protein.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=32428

gentile 3:42, September 11, 2005